Table 1:

Active or recently completed Immunotherapy Trials for PSP on Clinicaltrials.gov. PSPRS: PSP Rating Scale; FFP: Fresh Frozen Plasma.

Compound (Alternate name)	Company/Sponsor	Number of Patients	Phase	NCT number	Primary Outcome measures	Status/Results
ABBV-8E12 (C2N-8E12, HJ8.5)	AbbVie	142	Phase 2 Extension	NCT03391765	Change in PSPRS, up to 5 years	Active, not recruiting
		378	Phase 2	NCT02985879	Change in PSPRS, up to 1 year; Adverse events	Active, not recruiting
			Expanded Access	NCT03744546		Active, not recruiting
		3	Phase 1 Extension	NCT03413319	Adverse events	Active, not recruiting
		30	Phase 1	NCT02494024	Safety and Tolerability	Completed
BIIB092 (BMS-986168, IPN007)	Biogen	490	Phase 2	NCT03068468	Change in PSPRS, at 1 year; Adverse events	Active, not recruiting
		47	Phase 1 Extension	NCT02658916	Adverse events; Change in lab abnormalities, vital signs, ECGs, and physical exams	Active, not recruiting
		48	Phase 1	NCT02460094	Safety and Tolerability	Completed
UCB0107 (Antibody D)	UCB Biopharma	52 healthy males	Phase 1	NCT03464227	Adverse events	Completed
Autologous Bone Marrow Derived Stem Cells	MD Stem Cells	300**	Not applicable	NCT02795052	Activities of Daily Living, up to 1 year	Recruiting
FFP	University of California, San Francisco	6	Phase 1	NCT02460731	Drug limiting toxicity	Active, not recruiting

^**This study is not recruiting patients exclusively with PSP, but rather a wide range of conditions