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. Author manuscript; available in PMC: 2020 Dec 8.
Published in final edited form as: Matrix Biol. 2020 Sep 28;94:95–109. doi: 10.1016/j.matbio.2020.09.002

Figure 3. Chondroitin sulfate is identified as a major GAG subtype in the mineral matrix of mouse bone and is reduced in Bgn KO mice.

Figure 3.

(A) Agarose gel electrophoresis showed various subtypes of GAGs, heparin sulfate (HS), dermatan sulfate (DS), and chondroitin sulfate (CS). GAGs extracted from WT mouse bone matrix were examined and confirmed by chondroitinase ABC digestion. (B) GAGs from non-mineralized (Non-M) and mineralized (Mineral) compartments of WT and Bgn KO mice bone matrix were analyzed by agarose gel electrophoresis. CS was detected in mineralized bone matrix (left panel). The CS band intensity was quantified by NIH Image J software (right panel). n = 6-7. *p < 0.05.