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Relationship between thalamocortical connectivity to the Rolandic cortex and age among longitudinal subjects. Rather than increase with age as observed in controls (blue line indicates linear regression model fit and blue dotted lines indicate 95% confidence interval of cross-sectional controls, n = 19), in each longitudinal childhood epilepsy with centrotemporal spikes (CECTS) case available (n = 4), thalamocortical connectivity index (CI) to the Rolandic cortex decreased with age
