Figure 1: High levels of anti-NET antibodies among patients with primary APS.
A-B, Anti-NET IgG and IgM were measured in individuals with primary APS, SLE without antiphospholipid antibodies, unprovoked venous thrombosis without antiphospholipid antibodies, or no known disease (healthy controls). Levels of anti-NET IgG and IgM at 450-nm optical density (OD) were compared by Kruskal–Wallis test **p<0.01, ***p<0.001, and ****p<0.0001 as compared with the control group. C, The relationship between anti-NET IgG and anti-β2GPI IgG was assessed by Spearman’s correlation test and linear regression. D, Anti-NET IgG levels were measured in six patients with primary APS who had two to four years of follow-up in our clinic.