Scheme 2:
Reagents and conditions: (a) Bu2SnO, CH3OH, 70 °C, 3 h, then PMBCl, toluene, 60 °C, 14 h; (b) TBSCl, imidazole, DMF, r t, 16 h, 66 % in two steps; (c) BnBr, NaH, DMF, 0 °C, 2 h, 95%.
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