Skip to main content
. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: FASEB J. 2020 Aug 24;34(10):13900–13917. doi: 10.1096/fj.202001515R

Fig. 6: PKI genomic alterations are frequent in cancer and PKIA amplification is associated with aggressive prostate cancer.

Fig. 6:

A. TCGA PanCancer Atlas analysis of PKIA, PKIB, and PKIG gene alteration frequencies in human cancers. Cancer type (X-axis) is ordered by most common PKIA gene alteration frequency. B. cBioPortal analysis of the TCGA prostate adenocarcinoma PanCancer Atlas dataset for progression-free survival (months) between patients with PKIA gene alterations vs. those with unaltered PKIA. Significance (LogRank test and exact P value) calculated in cBioPortal. C. cBioPortal Log2 RNAseq analysis of PKIA mRNA expression vs. copy-number alteration of samples in the TCGA PanCancer Atlas prostate adenocarcinoma dataset.