FIGURE 3.

Inhibition of [Ca²⁺]_i blocks maresin 1 (MaR1)-stimulated high molecular weight glycoprotein secretion. Rat conjunctival goblet cells were incubated with the Ca²⁺ chelator BAPTA/AM and secretion measured for 2 hr in response to MaR1 (10⁻⁹ M) or the cholinergic agonist carbachol (Cch, 10⁻⁴ M). Data are mean ± SEM from three experiments. *significance above basal. BAPTA, 1,2-bis(o-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid; SEM, standard error of the mean