Figure 5. Plg-RKT null mice cannot successfully lactate.
Survival data are shown for a cohort of offspring of Plg-RKT+/+ (dashed lines) and Plg-RKT−/− (solid lines) primiparous female littermates: 48 offspring of Plg-RKT+/+ mice and 30 offspring of Plg-RKT−/− mice. **** P<0.0001 Log-rank (Mantel Cox) test]. This research was originally published in Miles, L.A., Baik, N., Bai, H., Makarenkova, H.P., Kiosses, W.B., Krajewski, S., Castellino, F.J., Valenzuela, A., Varki, N.M., Mueller, B.M., Parmer, R.J. The plasminogen receptor, Plg-RKT, is essential for mammary lobuloalveolar development and lactation. J Thromb Haemost. 2018, 16(5):919–932. and is reprinted with permission from John Wiley and Sons.