a) Connector hubs identified in the healthy control (HC)
group which correspond to ROIs with the highest participation
coefficient (PC) scores across the whole brain (>1SD above
the mean). b) Connector hubs identified for each variant group, top
to bottom: non-fluent (nfvPPA), logopenic (lvPPA), semantic (svPPA). Compared to
the HC, all three variants “lost” the left SFG and the left SPG
(circled) and the bilateral S/MTG are retained (circled). On the right panel the
new hubs (present in PPA but not in the HC) for each variant are shown.
SFG: superior frontal gyrus, SPG: superior parietal gyrus, S/MTG:
superior/middle and temporal gyri, MFG: middle frontal gyrus, MFG_DPFC:
middle frontal dorsal prefrontal cortex. ITG: inferior temporal gyrus, FuG:
fusiform gyrus, PrCG: precentral gyrus, PrCu: precuneus.