Table I.
First set (n=12) | Second set (n=28) | |||
---|---|---|---|---|
Variable | Early relapse | Remission | Early relapse | Remission |
Median age in years (range) | 0.3 (0.2–0.7) | 0.4 (0.0–0.6) | 4 (1–18) | 4 (1–16) |
Gender | ||||
Female | 3 | 5 | 5 | 8 |
Male | 3 | 1 | 9 | 6 |
KMT2A fusion partner | Positive | Positive | Negative | Negative |
ENL | 3 | 3 | 0 | 0 |
AF4 | 3 | 3 | 0 | 0 |
Relapse-free survival time (months) | 8.5 (1.4–19.3) | 51.4 (27.3–77.0) | 17 (8.4–36.5) | 83.4 (47.3–125.6) |
KMT2A: Lysine (K)- specific methyltransferase 2A gene; ENL: Eleven nineteen leukemia; AF4: ALL-1 fuse gene from chromosome 4.