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. 2020 Dec 8;10:35. doi: 10.1186/s13395-020-00255-0

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 13 — Inflammation and fibrosis in muscles of non-exercised 24-week-old WT, Nrf2^tKO, mdx, and Nrf2^tKOmdx mice. (a) Representative photos and (b) semi-quantitative analysis of inflammation in GM based on H&E staining; n = 4-6. (c) Representative photos and (d) semi-quantitative analysis of inflammation in diaphragm based on H&E staining; n = 5. (e) Representative photos and (f) semi-quantitative analysis of collagen deposition in GM based on Masson’s trichome staining; n = 5. (g) Representative photos and (h) semi-quantitative analysis of inflammation in diaphragm based on Masson’s trichome staining; n = 5-7. The data are presented as mean +/− SEM; ***p ≤ 0.001; ****p ≤ 0.0001, one-way ANOVA with Tukey’s post hoc test; the scale bars represent 100 μm