Supplemental Figure S6.

Transcriptional analysis of F4/80⁺ cells isolated from C105F/+ kidneys reveals an integrated stress response with ATF4 regulated gene expression. Heat map of the one-way hierarchical clustering using Z-score for normalized value between mutant (MT)/+/wild type of significantly up-regulated (yellow) or down-regulated (yellow) genes (log2 FD > 1 with P_adjusted < 0.05) using Benjamini-Hochberg correction for multiple comparisons. There were 220 genes satisfying with fc2 and raw.p. TG, transgenic or mutant genotype.