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. 2020 Dec;190(12):2436–2452. doi: 10.1016/j.ajpath.2020.08.015

Figure 7.

Figure 7

Kidney mononuclear phagocytic cell uptake of uromodulin. Immunofluorescence of uromodulin and mononuclear phagocyte (MP) marker colocalization in kidney sections from a 12-week–old mutant (mut)/+ mouse (A and B) and 12-week–old wild-type (WT) mouse 7 days following ischemia-reperfusion (IR) injury (C and D). Uromodulin indicates green signal (A and C) and purple signal (B and D); major histocompatibility complex II indicates red signal (A and C); and CD11c indicates green signal (B and D). Arrows indicate MPs with uptake of uromodulin. Scale bars: 10 μm (A, B, and D); 40 μm (C).