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CT scan and tumor markers of the patient experienced HPD after nivolumab treatment. (a) The CT scan before and after nivolumab treatment. In this case, HPD was defined as a disease condition after anti-PD1/PD-L1 treatment which has a short TTF (less than 1 month) and a more than 50% increase than baseline in the size of the lesion. (b) The alterations in tumor markers during nivolumab treatment
