Table 1.
Results of NGS examination
| Tissue sample |
Blood sample |
|||
|---|---|---|---|---|
| Gene | Abundance | Alteration type | Abundance | Alteration type |
| EGFR | CN: 4.55 | Amplification | ||
| TP53 | 44.60% | Exon 6, p.Y220C, missense | 7.20% | Exon 6, p.Y220C, missense |
| NOTCH1 | 57.73% | Exon 6, p.C359Y, missense | 4.72% | Exon 6, p.C359Y, missense |
| HLA-A | 55.20% | Exon 5, p.S337P, missense | 7.54% | Exon 5, p.S337P, missense |
| EP300 | 30.14% | Exon 28, p.W1509R, missense | 10.34% | Exon 28, p.W1509R, missense |
| ARID1A | 0.83% | Exon 7, non-sense | ||
| ASXL1 | 1.74% | Exon 12, p.P1035S, missense | ||
| PIK3CA | 1.94% | Exon 10, p.E545K, missense | ||
| HSD3B1 | 1.60% | Exon 4, p.Y181C, missense | ||
| PTCH1 | 1.93% | Exon 18, p.E970K, missense | ||
| FAT3 | 2.50% | Exon 9, p.T1874A, missense | ||
| LRP1B | 2.24% | Exon 18, p.D2621H, missense | ||
| FGF10 | 1.34% | Exon 10, p.V77F, missense | ||
| PPM1D | 0.57% | Exon 6, non-sense | ||
| SMAD4 | 1.29% | Exon 11, non-sense | ||
| TERT | 1.22% | Exon 9, p.R858Q, missense | ||