Table 1.
Characteristics of women with a primary invasive cervical cancer diagnosis 2002–2011 in Sweden by HPV status.
| Characteristics | PCR+ n = 2456 |
PCR− n = 394 |
||
|---|---|---|---|---|
| PCR− n = 394 |
PCR-/RNAseq− n = 223* |
PCR-/RNAseq+ n = 169* |
||
| Age, median (range) | 49 (18–98) | 62.5 (24–95) | 68 (30–93) | 57 (24–95) |
| Age at cancer diagnosis | ||||
| <29 | 165 (6.7) | 2 (0.5) | 0 (0.0) | 2 (1.2) |
| 30–44 | 860 (35.0) | 73 (18.5) | 24 (10.8) | 49 (29.0) |
| 45–59 | 608 (24.8) | 94 (23.9) | 51 (22.9) | 42 (24.9) |
| 60–74 | 428 (17.4) | 112 (28.4) | 70 (31.4) | 42 (24.9) |
| >74 | 395 (16.1) | 113 (28.7) | 78 (35.0) | 34 (20.1) |
| FIGO stage | ||||
| IA | 473 (19.3) | 57 (14.5) | 19 (8.5) | 38 (22.5) |
| IB | 1027 (41.8) | 130 (33.0) | 71 (31.8) | 59 (34.9) |
| II | 502 (20.4) | 75 (19.0) | 40 (17.9) | 34 (20.1) |
| III+ | 454 (18.5) | 132 (33.5) | 93 (41.7) | 38 (22.5) |
| Histological types | ||||
| Adenocarcinoma | 437 (17.8) | 91 (23.1) | 83 (37.2) | 7 (4.1) |
| Adenosquamous cell carcinoma | 97 (3.9) | 22 (5.6) | 21 (9.4) | 0 (0.0) |
| Other types | 68 (2.8) | 24 (6.1) | 22 (9.9) | 2 (1.2) |
| Squamous cell carcinoma | 1854 (75.5) | 257 (65.2) | 97 (43.5) | 160 (94.7) |
FIGO International Federation of Gynecology and Obstetrics.
*There were 2 specimens that had been HPV-negative by PCR but, had too little material available for sequencing and thus only 392/394 HPV-negative cancers were sequenced.