Table 3.
HPV detection using RNAseq in HPV PCR negative specimens.
| n (Total 392) | % Total (95% CI) | |
|---|---|---|
| HPV Negative by RNAseq | 223 | 56.89 (51.82–61.85) |
| HPV Positive by RNAseq | 169 | 43.11 (38.15–48.18) |
| HPV 16 | 4 | 1.02 (0.28–2.59) |
| HPV 18 | 1 | 0.26 (0.01–1.41) |
| HPV 31 | 19 | 4.85 (2.94–7.47) |
| HPV 32 | 1 | 0.26 (0.01–1.41) |
| HPV 33 | 58 | 14.80 (11.43–18.70) |
| HPV 34 | 3 | 0.77 (0.16–2.22) |
| HPV 35 | 3 | 0.77 (0.16–2.22) |
| HPV 38 | 1 | 0.26 (0.01–1.41) |
| HPV 39 | 8 | 2.04 (0.89–3.98) |
| HPV 42 | 2 | 0.51 (0.06–1.83) |
| HPV 45 | 17 | 4.34 (2.55–6.85) |
| HPV 52 | 2 | 0.51 (0.06–1.83) |
| HPV 53 | 2 | 0.51 (0.06–1.83) |
| HPV 54 | 1 | 0.26 (0.01–1.41) |
| HPV 56 | 8 | 2.04 (0.89–3.98) |
| HPV 58 | 8 | 2.04 (0.89–3.98) |
| HPV 59 | 4 | 1.02 (0.28–2.59) |
| HPV 66 | 1 | 0.26 (0.01–1.41) |
| HPV 68 | 1 | 0.26 (0.01–1.41) |
| HPV 70 | 1 | 0.26 (0.01–1.41) |
| HPV 73 | 23 | 5.87 (3.76–8.67) |
| HPV 82 | 1 | 0.26 (0.01–1.41) |
Number of HPV PCR negative specimens that turn HPV positive after being subjected to RNAseq. Highlighted with bold HPV genotypes are the types which present specific probes for the PCR-based detection method.