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. 2020 Dec 8;10:21466. doi: 10.1038/s41598-020-78511-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Bipartite graph visualizing the enriched mammalian genes with their associated DA microbes in PD versus healthy controls. Genes are charted as blue round nodes whereas DA microbes are plotted as red squares. The sizes of the nodes are proportional to the number of edges in the bipartite graph whereas the width of the edges indicates the strength of the enrichment measured by combined scores from the MSEA algorithm.