Fig. 2. Correlation and trajectory of Aβ_1-42 uptake by monocyte subsets relative to age.

Spearman correlation analysis was utilized to investigate the correlation between age and the uptake of Aβ_1-42 by all monocytes (A), by the CD14⁺CD16⁻ subset (B), by the CD14⁺CD16⁺ subset (C) and by the CD14^dimCD16⁻ subset (D). E The trajectory of Aβ_1-42 uptake by total monocytes, CD14^dimCD16⁺ and the CD14⁺CD16⁻ subsets relative to age was modelled using Fit spline/Lowess (cubic) spline. n = 104. MONO monocytes, Aβ amyloid-β protein.