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. 2020 Dec 8;10:21491. doi: 10.1038/s41598-020-77990-3

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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A2 and A3 treatment inhibits production of cytokines from uninfected cells. The protein expression levels of IFNγ, IL1α, IL1β, IL2, IL4, IL6, IL10, IL12 p10, and TNFα in U87MG cells that were overlaid with supernatants from HMC3 cells, reported as concentration in pg/mol compared to untreated control. Limit of detection depicted by gray line; n = 1.