Table 2.
Distribution of post-transplant malignancies.
| Type of cancer | Number of cancer (%) | Age at transplant, years* | Age at diagnosis of PTM, years* | Time between transplant and PTM, years* | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Male | Female | Total | Male | Female | Total | Male | Female | Total | Male | Female | Total | |
| Thyroid | 30 (8.8) | 55 (21.4) | 85 (14.2) | 44.5 (38.8–54.8) | 44.0 (36.0–50.0) | 44.0 (37.0–52.0) | 48.5 (43.0–56.8) | 46.0 (41.0–53.0) | 48.0 (42.0–55.0) | 2.7 (1.8–6.5) | 4.0 (2.1–6.6) | 3.4 (1.8–6.5) |
| Colorectal | 34 (10.0) | 33 (12.8) | 67 (11.2) | 46.5 (39.3–56.5) | 47.0 (34.0–54.0) | 47.0 (36.5–55.0) | 52.5 (45.3–59.0) | 51.0 (38.0–59.0) | 52.0 (42.0–59.0) | 3.9 (2.3–8.2) | 4.5 (2.2–8.5) | 4.4 (2.2–8.4) |
| Kidney | 46 (13.5) | 18 (7.0) | 64 (10.7) | 44.0 (37.3–52.8) | 45.0 (36.5–53.0) | 45.0 (36.8–53.0) | 51.0 (41.3–59.0) | 53.0 (43.3–58.3) | 51.5 (41.8–59.0) | 6.1 (2.4–9.1) | 3.6 (2.1–8.2) | 5.8 (2.3–9.0) |
| Stomach | 31 (9.1) | 22 (8.6) | 53 (8.9) | 52.0 (47.0–55.5) | 52.0 (46.0–58.0) | 52.0 (46.0–58.0) | 57.0 (49.5–62.0) | 56.0 (51.3–62.0) | 57.0 (51.0–62.0) | 5.2 (3.3–7.0) | 4.8 (2.7–6.5) | 5.0 (3.3–6.8) |
| Prostate | 49 (14.4) | 0 (0.0) | 49 (8.2) | 52.0 (45.0–58.0) | - | 52.0 (45.0–58.0) | 55.0 (49.0–60.0) | - | 55.0 (49.0–60.0) | 3.6 (1.3–6.4) | - | 3.6 (1.3–6.4) |
| Liver | 32 (9.4) | 10 (3.9) | 42 (7.0) | 51.0 (45.8–55.0) | 49.5 (31.5–51.5) | 49.5 (40.3–54.8) | 54.5 (47.0–59.0) | 45.5 (35.0–56.0) | 53.5 (45.3–58.8) | 3.3 (1.7–6.0) | 2.7 (1.8–4.6) | 3.2 (1.8–5.7) |
| Lung | 31 (9.1) | 11 (4.3) | 42 (7.0) | 54.0 (45.5–59.0) | 53.5 (41.0–55.0) | 53.5 (42.8–58.0) | 59.0 (49.0–63.5) | 53.0 (44.0–58.5) | 58.0 (47.3–62.8) | 4.3 (2.7–6.0) | 3.8 (1.0–5.3) | 4.2 (1.9–5.5) |
| Breast | 1 (0.3) | 35 (13.6) | 36 (6.0) | 51.0 (51.0–51.0) | 44.0 (39.5–50.0) | 44.0 (39.8–50.3) | 57.0 (57.0–57.0) | 48.0 (44.5–53.0) | 48.0 (44.8–53.8) | 6.3 (6.3–6.3) | 4.1 (2.2–5.8) | 4.2 (2.3–6.0) |
| Non-Hodgkin lymphoma | 13 (3.8) | 14 (5.4) | 27 (4.5) | 32.0 (29.0–47.0) | 45.0 (39.8–52.0) | 45.0 (31.5–51.0) | 38.0 (35.0–49.0) | 53.0 (41.8–57.3) | 49.0 (37.0–55.0) | 3.3 (1.6–9.0) | 5.3 (2.4–7.1) | 5.1 (1.7–7.8) |
| Urinary bladder | 13 (3.8) | 7 (2.7) | 20 (3.3) | 52.0 (39.0–55.0) | 48.5 (41.5–51.0) | 48.5 (38.8–54.3) | 54.0 (48.0–57.0) | 51.0 (48.0–54.5) | 53.5 (47.8–57.0) | 5.8 (2.5–8.7) | 5.3 (2.7–6.2) | 5.4 (2.4–8.1) |
| Cervix | 0 (0.0) | 14 (5.4) | 14 (2.3) | - | 39.5 (37.0–45.3) | 39.5 (37.0–45.3) | - | 44.5 (41.0–49.8) | 44.5 (41.0–49.8) | - | 3.8 (2.3–6.0) | 3.8 (2.3–6.0) |
| Non-melanoma skin | 9 (2.6) | 4 (1.6) | 13 (2.2) | 54.0 (44.0–59.0) | 54.0 (49.8–58.0) | 54.0 (44.0–59.0) | 61.0 (52.0–66.0) | 56.5 (53.5–62.3) | 59.0 (52.0–66.0) | 7.4 (4.3–8.9) | 5.1 (4.1–6.6) | 7.2 (4.3–8.9) |
| Oral cavity | 9 (2.6) | 4 (1.6) | 13 (2.2) | 46.0 (40.0–48.0) | 46.0 (36.0–41.5) | 46.0 (37.0–48.0) | 50.0 (41.0–53.0) | 41.0 (39.3–43.5) | 47.0 (41.0–51.0) | 2.8 (1.9–4.9) | 3.1 (1.7–4.6) | 2.8 (1.8–4.9) |
| Pancreas | 9 (2.6) | 2 (0.8) | 11 (1.8) | 57.0 (54.0–61.0) | 57.0 (37.5–54.5) | 57.0 (53.5–62.0) | 60.0 (56.0–61.0) | 50.0 (42.0–58.0) | 60.0 (54.5–63.5) | 2.8 (0.9–3.5) | 4.3 (3.6–4.9) | 2.9 (1.0–3.6) |
| Leukaemia | 6 (1.8) | 5 (1.9) | 11 (1.8) | 47.0 (41.0–50.8) | 47.0 (33.0–48.0) | 47.0 (36.0–50.0) | 50.0 (44.3–54.3) | 46.0 (37.0–53.0) | 48.0 (40.0–53.5) | 3.7 (2.3–5.5) | 4.4 (1.6–6.7) | 4.2 (1.8–6.3) |
| Nasopharyngeal | 8 (2.3) | 2 (0.8) | 10 (1.7) | 49.5 (47.0–53.0) | 49.0 (48.3–48.8) | 49.0 (48.3–52.3) | 53.0 (49.0–57.3) | 51.0 (50.0–52.0) | 52.5 (49.5–56.3) | 3.5 (2.4–5.8) | 3.2 (2.4–4.1) | 3.5 (1.8–5.0) |
| Kaposi sarcoma | 8 (2.3) | 1 (0.4) | 9 (1.5) | 42.5 (33.0–55.5) | 46.0 (63.0–63.0) | 46.0 (34.0–57.0) | 47.0 (34.0–57.0) | 65.0 (65.0–65.0) | 55.0 (35.0–60.0) | 2.2 (1.1–5.0) | 2.4 (2.4–2.4) | 2.4 (1.1–4.2) |
| Ovarian | 0 (0.0) | 8 (3.1) | 8 (1.3) | – | 44.5 (40.0–50.8) | 44.5 (40.0–50.8) | – | 50.5 (43.8–53.8) | 50.5 (43.8–53.8) | – | 3.5 (2.9–5.2) | 3.5 (2.9–5.2) |
| Uterus | 0 (0.0) | 7 (2.7) | 7 (1.2) | – | 52.0 (36.0–55.5) | 52.0 (36.0–55.5) | – | 55.0 (42.5–56.0) | 55.0 (42.5–56.0) | – | 4.7 (1.9–7.0) | 4.7 (1.9–7.0) |
| Gallbladder | 5 (1.5) | 1 (0.4) | 6 (1.0) | 56.0 (51.0–57.0) | 53.5 (49.0–49.0) | 53.5 (49.5–56.8) | 58.0 (52.0–61.0) | 56.0 (56.0–56.0) | 57.0 (53.0–60.3) | 1.7 (1.7–3.2) | 7.1 (7.1–7.1) | 2.5 (1.7–5.3) |
| Ureter | 1 (0.3) | 3 (1.2) | 4 (0.7) | 56.0 (56.0–56.0) | 52.5 (48.5–54.5) | 52.5 (48.8–57.0) | 61.0 (61.0–61.0) | 58.0 (56.0–63.5) | 59.5 (57.0–63.0) | 5.3 (5.3–5.3) | 9.6 (7.3–10.0) | 7.5 (5.2–9.8) |
| Oesophagus | 2 (0.6) | 1 (0.4) | 3 (0.5) | 57.5 (55.3–59.8) | 58.0 (58.0–58.0) | 58.0 (55.5–60.0) | 67.0 (66.0–68.0) | 65.0 (65.0–65.0) | 65.0 (65.0–67.0) | 9.6 (8.4–10.9) | 7.1 (7.1–7.1) | 7.2 (7.2–9.6) |
| Central nervous system | 2 (0.6) | 0 (0.0) | 2 (0.3) | 53.5 (51.3–55.8) | – | 53.5 (51.3–55.8) | 55.5 (53.8–57.3) | – | 55.5 (53.8–57.3) | 2.3 (1.7–2.9) | – | 2.3 (1.7–2.9) |
| Melanoma | 1 (0.3) | 0 (0.0) | 1 (0.2) | 36.0 (36.0–36.0) | – | 36.0 (36.0–36.0) | 40.0 (40.0–40.0) | – | 40.0 (40.0–40.0) | 4.2 (4.2–4.2) | – | 4.2 (4.2–4.2) |
| Hodgkin lymphoma | 1 (0.3) | 0 (0.0) | 1 (0.2) | 53.0 (53.0–53.0) | – | 53.0 (53.0–53.0) | 53.0 (53.0–53.0) | – | 53.0 (53.0–53.0) | 0.8 (0.8–0.8) | – | 0.8 (0.8–0.8) |
*Data are expressed as median and interquartile range.