Table 1.

Overview of differences in quantitative proteome of ApoE- and LDLR-deficient platelets as compared to wild-type platelets. Highly purified platelets from wild-type, Apoe^−/− and Ldlr^−/− mice were subjected to label-free proteomics analysis. Ratios of 1,533 unique proteins were quantified by mass spectrometry (see “Methods”). Unique proteins of the quantitative proteome were assigned to 22 assumed function classes. Green represents > 1.5 fold downregulated and red > 1.5-fold upregulated proteins. N = 3–4 animals/group.