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. Author manuscript; available in PMC: 2020 Dec 8.
Published in final edited form as: Vaccine. 2015 Mar 21;33(18):2167–2174. doi: 10.1016/j.vaccine.2015.02.067

FIGURE 1. Vaccination protocols.

FIGURE 1.

The cartoon is an adaptation from Virnik et al. [19] and details the vaccination timeline used for this Indian rhesus macaque study. Animals CL6A and CL6J had received RA27/3 rubella vaccine strains and sham DNA. Macaques CL67, CL49, CL6V had received rubella type 1 and type 2 which were “no takes” and did not induce antibodies to rubella and also did not induce Gag-specific T cell immunity. The animals received sequential vaccinations with DNA and rubella vector type 3 or type 3*, referred to as rubella vector herein, expressing SIV Gag. The animals were analyzed for Gag-specific IFN-γ+ T cell responses, and macaques positive for the MamuA*01 haplotype were also analyzed for Gag CM9 tetramer responses.