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. 2020 Sep 24;123(12):1749–1756. doi: 10.1038/s41416-020-01087-x

Fig. 2. Validation of the role of farnesyltransferase depletion in resistance to sunitinib in ccRCC.

Fig. 2

a Western blot analysis of the indicated ccRCC cells transfected with pooled faranesyltransferase β subunit (FNTB) siRNA. Negative controls include Non targeting siRNA (NT siRNA) and mock transfection (Mock). b Analysis of sunitinib-mediated apoptosis in the indicated ccRCC cells transfected with FNTB siRNA and Non targeting siRNA. The percentage of apoptotic cells is indicated in the histograms. The representative data of one out of three independent experiments are presented.