TABLE 5.
A summary of newly discovered crude extracts as α‐glucosidase and α‐amylase inhibitors
No. | Variety | Part used | Active compounds | Inhibited enzyme | Enzyme origin | Method | IC50 | Reference |
---|---|---|---|---|---|---|---|---|
1 | Purple pigmented | Kernel | Water extracts | α‐Glucosidase | Baker's yeast | pNPG | Ranilla et al. (2008) | |
Yellow, purple‐red mottled | Kernel | Water extracts | α‐Glucosidase | Baker's yeast | pNPG | |||
Yellow, red blotched | Kernel | Water extracts | α‐Glucosidase | Baker's yeast | pNPG | |||
Half yellow‐half red | Kernel | Water extracts | α‐Glucosidase | Baker's yeast | pNPG | |||
Purple mottled | Kernel | Water extracts | α‐Glucosidase | Baker's yeast | pNPG | |||
2 | Sorghum (Mongdang‐susu(SS‐1)) | Whole grains | Ethanol extracts | α‐Amylase | Porcine | DNSA | 4.5 ± 0.0 μg/ml | Kim et al. (2011) |
α‐Amylase | Saliva | DNSA | 6.1 ± 0.4 μg/ml | |||||
α‐Glucosidase | Bacillus stearothermophilus | pNPG | 1.1 μg/ml | |||||
Sorghum (Me‐susu(SS‐2)) | Whole grains | Ethanol extracts | α‐Amylase | Porcine | DNSA | 2.9 ± 0.5 μg/ml | ||
α‐Amylase | Saliva | DNSA | 4.5 ± 0.2 μg/ml | |||||
α‐Glucosidase | Bacillus stearothermophilus | pNPG | 1.2 μg/ml | |||||
Sorghum (Susongsaengi‐susu (SS‐3)) | Whole grains | Ethanol extracts | α‐Amylase | Porcine | DNSA | 11.8 ± 0.1 μg/ml | ||
α‐Amylase | Saliva | DNSA | 10.3 ± 0.0 μg/ml | |||||
α‐Glucosidase | Bacillus stearothermophilus | pNPG | 1.3 μg/ml | |||||
Sorghum (Sikyung‐susu (SS‐4)) | Whole grains | Ethanol extracts | α‐Amylase | Porcine | DNSA | 9.0 ± 0.4 μg/ml | ||
α‐Amylase | Saliva | DNSA | 10.2 ± 0.4 μg/ml | |||||
α‐Glucosidase | Bacillus stearothermophilus | pNPG | 1.4 μg/ml | |||||
Sorghum (Jangsu‐susu (SS‐5)) | Whole grains | Ethanol extracts | α‐Amylase | Porcine | DNSA | 194.1 ± 3.1 μg/ml | ||
α‐Amylase | Saliva | DNSA | 333.3 ± 5.0 μg/ml | |||||
α‐Glucosidase | Bacillus stearothermophilus | pNPG | 20.4 μg/ml | |||||
Sorghum (Heuin‐susu (SS‐ 6)) | Whole grains | Ethanol extracts | α‐Amylase | Porcine | DNSA | >666 μg/ml | ||
α‐Amylase | Saliva | DNSA | >666 μg/ml | |||||
α‐Glucosidase | Bacillus stearothermophilus | pNPG | 102.7 μg/ml | |||||
3 | 13 kind of barely | Seed | Hot water, cold water, and ethanol extracts | α‐Amylase | DNSA | Ramakrishna et al. (2017) | ||
α‐Glucosidase | pNPG |