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. 2020 Dec 4;13:3257–3268. doi: 10.2147/JPR.S286771

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© 2020 Hsu et al.

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Implantation of stem cell exosome-scaffold on ligated nerves suppresses L5/6 spinal nerve ligation (SNL)-induced inflammation on day 7 after surgery. (A) Representative immunofluorescent image showing the expression of TNF-α, IL-1β, IL-10 and GDNF in ipsilateral L5 DRG. The white spots are DAPI nuclear staining. Scale bar: 50 μm. (B) Left: representative Western blots of TNF-α, IL-1β, IL-10, GDNF and control protein actin in ipsilateral L5/6 DRG. Right: summarized graph depicting protein levels presented as raw data points and Mean ± SD, taking Sham/saline-scaffold group as 100% (*P<0.05, **P<0.01, Kruskal–Wallis test followed by Dunn’s multiple pairwise comparisons test, n=3 in each group).