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. 2020 Oct 30;11:575009. doi: 10.3389/fphar.2020.575009

TABLE 2.

2-years survival, 95% confidence intervals and log-rank test for EFS and OS for all variables analyzed, for the whole cohort of patients.

n EFS OS
2-year survival 95% CI p-value 2-year survival 95% CI p-value
All patients 67 56.6 44.2 72.5 79.2 67.4 93.2
Type 1st CR 44 60.7 44.9 82.0 0.21 80.2 65.1 98.8 0.40
Primary refractory 23 47.1 29.4 75.3 77.2 59.6 100.0
Gender Female 29 44.0 27.0 71.4 0.023 76.2 59.1 98.3 0.50
Male 38 66.6 51.4 86.3 82.2 67.0 100.0
Age at diagnosis <4 years 42 73.3 60.9 88.2 0.013 78.3 63.6 96.4 0.26
≥4 years 25 20.6 6.7 63.9 81.0 62.8 100.0
MYCN Amplified 12 50.0 28.4 88.0 0.35 50.9 24.6 100.0 0.088
Not amplified 54 58.5 44.8 76.5 85.7 74.1 99.0
Cycles 5 or less 14 40.0 20.2 79.2 0.12 92.9 80.3 100.0 0.55
More than 5 53 63.1 49.9 79.7 72.1 56.2 92.4
Previous ASCT No 54 54.2 40.1 73.2 0.28 84.1 72.2 97.9 0.81
Yes 13 64.1 40.2 100.0 66.7 42.0 100.0
Previous RDT No 27 58.6 37.3 91.9 0.55 91.2 80.2 100.0 0.65
Yes 40 54.8 40.5 74.2 75.6 60.9 93.9
MRD No 51 53.9 39.6 73.3 0.58 73.3 58.9 91.1 0.21
Yes 16 64.6 43.6 95.8 100.0 100.0 100.0