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. 2020 Oct 30;11:575009. doi: 10.3389/fphar.2020.575009

TABLE 3.

2-years survival, 95% confidence intervals and log-rank test for EFS and OS for all variables analyzed. First CR patients only.

n EFS OS
2-year survival 95% CI p-value 2-year survival 95% CI p-value
All patients 44 60.7 44.9 82.0 80.2 65.1 98.8
Gender Female 19 44.9 24.6 82.1 0.056 79.5 60.2 100.0 0.60
Male 25 74.0 55.1 99.2 79.5 57.7 100.0
Age at diagnosis < 1.6 years 5 80.0 51.6 100.0 0.48 100.0 100.0 100.0 0.26
≥ 1.6 years 39 57.2 40.0 81.8 76.5 59.3 98.8
MYCN Amplified 10 60.0 36.2 99.5 0.58 56.3 27.9 100.0 0.12
Not Amplified 34 61.6 43.5 87.2 89.6 75.8 100.0
Cycles 5 or less 10 45.0 21.1 96.1 0.36 90.0 73.2 100.0 0.73
More than 5 34 68.6 52.2 90.0 72.1 50.9 100.0
Previous ASCT No 33 58.7 39.9 86.3 0.48 85.4 69.5 100.0 0.63
Yes 11 65.5 38.9 100.0 71.4 44.7 100.0
Previous RT No 23 63.1 40.7 97.8 0.58 95.7 87.7 100.0 0.37
Yes 21 58.3 39.1 87.0 69.8 48.4 100.0
MRD No 38 58.9 41.4 83.8 0.87 77.5 61.0 98.6 0.38
Yes 6 66.7 37.9 100.0 100.0 100.0 100.0