Table 5.

Hospitalisation for COVID-19 and severe COVID-19 in the safety population

	ChAdOx1 nCoV-19 (n=12 021)	MenACWY or saline control (n=11 724)
Hospitalisation (WHO clinical progression score ≥4)
≤21 days after the first dose	2*	6
>21 days after the first dose and ≤14 days after the second dose	0	5
>14 days after the second dose	0	5
Severe COVID-19 (WHO clinical progression score ≥6)
≤21 days after the first dose	0	0
>21 days after the first dose and ≤14 days after the second dose	0	1
>14 days after the second dose	0	1

The safety population includes all randomisation participants who received at least one dose of vaccine. Severe COVID-19 (WHO score ≥6) is a subset of hospitalisations (WHO score ≥4). Cases were eligible for inclusion in efficacy if the first symptom or first NAAT-positive result was on or before the data cutoff date (Nov 4, 2020). Two cases appear in this table that do not appear in the table for serious adverse events in appendix 1 (pp 15–20) as the adverse event reporting date was after the data cutoff date. MenACWY=meningococcal group A, C, W, and Y conjugate vaccine. NAAT=nucleic acid amplification test.

^*One case on the day of the first vaccination and one case 10 days after the first dose.