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. Author manuscript; available in PMC: 2020 Dec 8.
Published in final edited form as: J Physiol. 2020 Mar 23;598(8):1491–1503. doi: 10.1113/JP279230

Figure 4. MAP and HR responses evoked by static muscle contraction and arterial injection of αβ-me ATP.

Figure 4.

A, static muscle contraction was evoked by electrical stimulation of the L4 and L5 ventral roots. Muscle tension induced by static muscle contraction was similar among the groups. Compared with that in control rats (n = 8), the MAP response was exaggerated in PAD rats (n = 6). HT significantly attenuated the amplification of the MAP response in PAD + HT rats (n = 5). *P < 0.05 vs. control rats; **P < 0.05 vs. PAD rats. No significant difference was found in the HR response among the groups. B, with administration of the same dosage of αβ-me ATP (0.125 nM), the enhancement in MAP was greater in PAD rats (n = 6) than in control rats (n = 5). *P < 0.05 vs. control rats. A significant attenuation of MAP enhancement was observed in PAD rats exposed to HT (n = 8). **P < 0.05 vs. PAD rats not exposed to HT.