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. 2020 Nov 11;47(1):171–182. doi: 10.3892/ijmm.2020.4788

Figure 5.

Figure 5

LINC00473 activates the Akt/Bad/Bcl-2 signaling pathway in Dex-stimulated hBMSCs. The results of western blot analysis revealed (A) the protein expression levels of p-Akt, Akt, p-Bad, Bad, Bcl-2 and cleaved caspase-3 in each group, and (B) the quantification of integrated density in target bands by normalization to GAPDH. All data are presented as the mean value ± standard deviation of 3 independent experiments. *P<0.05 compared with the normal group, #P<0.05 compared with the Dex group and the Dex + Vector group, &P<0.05 compared with the Dex + LINC00473-up group. LINC00473, lncRNA-00473; Akt, protein kinase B; Bad, Bcl-2-associated death promoter; Bcl-2, B-cell lymphoma 2; hBMSCs, human bone marrow-derived mesenchymal stem cells; Dex, dexamethasone.