Table 3. Multivariant binary logistic analysis for urinary microvesicles predicting diabetic nephropathy.
| Univariant | Multivariant | ||||||
|---|---|---|---|---|---|---|---|
| OR | 95% CI | P | OR | 95% CI | P | ||
| Podocyte MVs | |||||||
| lg(nephrin+) | 6.0 | 2.3–16.0 | <0.001 | 134.5 | 2.7–6801.3 | 0.014 | |
| lg(podocin+) | 5.1 | 1.9–13.7 | 0.001 | 3.0 | 0.1–103.4 | 0.544 | |
| lg(nephrin+ podocin+) | 3.6 | 1.7–7.8 | 0.001 | 0.02 | 0.001–1.3 | 0.068 | |
| Proximal tubular MVs | |||||||
| lg(AQP1+) | 3.0 | 1.3–6.8 | 0.009 | 0.5 | 0.1–4.4 | 0.547 | |
| lg(megalin+) | 2.9 | 1.3–6.3 | 0.007 | 1.0 | 0.2–5.5 | 0.979 | |
| lg(AQP1+ megalin+) | 2.2 | 1.2–4.0 | 0.011 | 1.5 | 0.3–6.9 | 0.620 | |
| Endothelial MVs | |||||||
| lg(CD31+) | 1.8 | 0.8–3.9 | 0.158 | ||||
| lg(CD144+) | 2.4 | 1.2–4.7 | 0.016 | 1.2 | 0.3–4.5 | 0.808 | |
| lg(CD31+ CD144+) | 1.7 | 0.8–3.6 | 0.167 | ||||
P values <0.05 are shown in bold. DN, diabetic nephropathy; AQP1, aquaporin 1; MVs, microvesicles; lg, log10; CI, confidence interval; OR, odds ratio.