Table 2. Risk factors for active bleeding.
Factors | Univariable analysis | Multivariable analysis | |||
---|---|---|---|---|---|
OR (95% CI) | P value | OR (95% CI) | P value | ||
Age >65 years | 1.733 (0.148–20.323) | 0.661 | 1.192 (0.033–43.518) | 0.924 | |
Male | 0.605 (0.051–7.215) | 0.691 | 0.435 (0.008–23.574) | 0.683 | |
Smoking | 0.620 (0.053–7.240) | 0.703 | – | – | |
Diabetes | 0.667 (0.057–7.788) | 0.746 | – | – | |
BMI | 0.701 (0.447–1.100) | 0.122 | 0.507 (0.207–1.242) | 0.137 | |
AA-induced platelet aggregation | 0.991 (0.930–1.057) | 0.792 | – | – | |
ADP-induced platelet aggregation | 0.981 (0.926–1.038) | 0.501 | – | – | |
Use of ticagrelor | 1.103 (0.655–1.827) | 0.705 | – | – | |
Hb | 1.027 (0.956–1.104) | 0.463 | – | – | |
Hct | 1.092 (0.841–1.416) | 0.509 | – | – | |
PLT count | 0.996 (0.976–1.018) | 0.746 | – | – | |
MPV | 1.305 (0.502–3.391) | 0.584 | – | – | |
PCT | 0.372 (0.000–442.129) | 0.923 | – | – | |
PDW | 1.139 (0.779–1.665) | 0.503 | – | – | |
Plasma miR-223 | 1.393 (0.979–1.982) | 0.066 | 1.864 (0.979–3.551) | 0.058 |
Log2 transformation was applied to miRNA data. BMI, body mass index; AA, arachidonic acid; ADP, adenosine diphosphate; Hb, hemoglobin; Hct, hematocrit; PLT, platelet; MPV, mean platelet volume; PCT, plateletcrit; PDW, platelet distribution width.