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. 2020 Nov;8(21):1365. doi: 10.21037/atm-20-3848

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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LINC00844 expression was significantly decreased in HCC tissue compared with corresponding adjacent non-tumor tissue (A). Suppressed expression of LINC00844 was correlated with portal vein invasion (B), number of tumor sites ≥3 (C), and AFP ≥400 ng/mL (D). Kaplan-Meier analysis showed that patients with lower LINC00844 expression had a higher rate of HCC recurrence than those with higher LINC00844 expression (E). This trend was maintained in patients regardless of whether they fell within (F) or beyond the Milan criteria (G). LINC00844, long non-coding RNA00844; HCC, hepatocellular carcinoma; AFP, α-fetoprotein.