Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Nov;8(21):1365. doi: 10.21037/atm-20-3848

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

PMC Copyright notice

Gene Ontology analysis indicated LINC00844 was involved in biological processes related to cancer pathogenesis, such as metabolic processes, protein binding, and cell cycle, growth, and death (A). KEGG pathway analysis indicated that LINC00844 inactivated the MAPK signaling pathway (B). Western blotting showed that MEK and ERK 1/2 phosphorylation were inhibited in LINC00844 overexpression cells (C), but were promoted in LINC00844 siRNA transfection cells (D). LINC00844, long non-coding RNA00844; KEGG, Kyoto Encyclopedia of Genes and Genomes pathway; MAPK, mitogen-activated protein kinase; MEK, mitogen activated kinase; ERK, extracellular signal-regulated kinase.