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. 2020 Nov;8(21):1409. doi: 10.21037/atm-20-2788

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Transplantation of M2b macrophages alleviated myocardial fibrosis after I/R injury. (A) Histopathological features of collagen deposition based on the Sirius red staining of heart sections from a rat model (18× and 160×); (B) quantification of the Sirius red staining (n=5 for the SO group and n=10 for the CK group and the MT group); (C) myocardial mRNA expression of collagen I, collagen III, TGF-β, CCN2 and HGF in the different groups (n=5 for the SO group, n=6 for the CK group, and n=10 for the MT group). *, P˂0.05; **, P˂0.01.