Table 2. Comparison of baseline and clinical characteristics of subjects according to the H-FABP levels (ng/mL).
| Variables | Quartile 1 (<1.50) | Quartile 2 (1.50–2.20) | Quartile 3 (2.21–3.00) | Quartile 4 (>3.00) | P value |
|---|---|---|---|---|---|
| Baseline characteristics | |||||
| Patients | 1,134 | 1,091 | 1,147 | 998 | |
| Age (years) | 54.2±9.0 | 57.2±8.9 | 59.0±9.3 | 62.9±9.6 | <0.001 |
| Male | 798 (70.4) | 781 (71.6) | 824 (71.8) | 684 (68.5) | 0.329 |
| BMI (kg/m2) | 25.83±2.95 | 25.89±3.15 | 25.88±3.09 | 26.12±3.39 | 0.166 |
| Hypertension | 703 (62.0) | 678 (62.1) | 752 (65.6) | 733 (73.4) | <0.001 |
| Dyslipidemia | 1,016 (89.6) | 1,003 (91.9) | 1,035 (90.2) | 891 (89.3) | 0.161 |
| Diabetes | 602 (53.1) | 599 (54.9) | 651 (56.8) | 549 (55.0) | 0.376 |
| Current Smokers | 337 (29.7) | 374 (34.3) | 357 (31.1) | 277 (27.8) | 0.011 |
| Peripheral vascular disease | 10 (0.9) | 15 (1.4) | 14 (1.2) | 20 (1.8) | 0.156 |
| Cerebrovascular disease | 24 (2.1) | 35 (3.2) | 36 (3.1) | 41 (4.1) | 0.070 |
| Family history of CAD | 172 (15.2) | 179 (16.4) | 154 (13.4) | 106 (10.6) | 0.001 |
| Laboratory data | |||||
| Triglyceride (mmol/L) | 1.85±1.43 | 1.78±1.10 | 1.79±1.12 | 1.76±1.26 | 0.403 |
| TC (mmol/L) | 4.14±1.23 | 4.15±1.12 | 4.14±1.20 | 4.12±1.12 | 0.923 |
| LDL (mmol/L) | 2.52±1.06 | 2.55±1.07 | 2.49±0.91 | 2.47±0.94 | 0.231 |
| HbA1c (%) | 6.39±1.17 | 6.47±1.23 | 6.53±1.17 | 6.78±1.31 | <0.001 |
| Troponin I (ng/mL) | 0.003 (0.001–0.007) | 0.004 (0.002–0.008) | 0.004 (0.002–0.010) | 0.006 (0.002–0.013) | <0.001 |
| Creatinine (μmol/L) | 73.75±14.38 | 75.40±13.59 | 77.16±15.30 | 85.65±22.34 | <0.001 |
| Treatments in hospital | |||||
| Aspirin | 1,099 (96.9) | 1,068 (96.9) | 1,106 (96.4) | 969 (97.1) | 0.224 |
| β-Blokers | 895 (78.9) | 847 (77.6) | 911 (79.4) | 764 (76.6) | 0.369 |
| Lipid-lowering medication | 1041 (91.8) | 1010 (92.6) | 1065 (92.9) | 942 (94.4) | 0.134 |
| ACEI or ARB | 478 (42.1) | 481 (44.1) | 537 (46.8) | 528 (52.9) | <0.001 |
| Multi-vessel disease ≥3 | 412 (36.2) | 436 (40.1) | 472 (41.3) | 430 (43.1) | 0.012 |
| Gensini score | 31.9±30.3 | 33.8±31.2 | 34.7±30.8 | 37.9±35.7 | <0.001 |
| Cardiovascular events | 66 (5.8) | 81 (7.4) | 93 (8.3) | 113 (11.3) | <0.001 |
Values are expressed as the mean ± SD, the median with interquartile range or n (%). CAD, coronary artery disease; BMI, Body mass index; TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; HbA1c, glycated hemoglobin; H-FABP, heart-fatty acid binding protein; TnI, troponin I; ACEI, angiotensin converting enzyme inhibitors; ARB, angiotensin receptor blocker.