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. 2020 Nov;8(21):1395. doi: 10.21037/atm-20-603

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2020 Annals of Translational Medicine. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Validation of the identified chemoresistance ncRNAs in cancer cell lines. (A, left) miR-92a-3p classified cancer cell lines into sensitive or resistant to tamoxifen (Wilcoxon rank-sum test, P=0.0014). (A, right) Target genes of miR-92a-3p were closely connected to targets of tamoxifen in PPI network. (B, left) miR-92a-3p classified cancer cell lines into sensitive or resistant to paclitaxel (Wilcoxon rank-sum test, P=0.0032). (B, right) Target genes of miR-92a-3p were closely connected to targets of paclitaxel in PPI network. (C) Significantly enriched KEGG pathways of miR-92a-3p. PPI, protein-protein interaction.