Table 1.
Demographics and clinical characteristics of patients with diarrhea-predominant irritable bowel syndrome and healthy controls
|
Features
|
IBS-D patients
|
Controls
|
P
value
|
| n | 55 | 28 | NA |
| Age in yr | 35.1 ± 9.8 | 34.4 ± 10.6 | 0.754 |
| Gender, male: Female | 41: 14 | 5: 2 | 0.761 |
| Body mass index in kg/m2 | 23.3 ± 3.4 | 22.6 ± 3.1 | 0.335 |
| Duration of disease in yr | 3.0 (1.5, 7.0) | NA | NA |
| Defecation frequency | 3.5 (2.5, 4.0) | 1.0 (0.7, 1.0) | < 0.001 |
| BSFS score | 5.5 (5.0, 6.0) | 4.0 (4.0, 4.0) | < 0.001 |
| IBS-SSS | 180.0 (150.0, 240.0) | NA | NA |
| Abdominal pain severity | 40.0 (20.0, 50.0) | NA | NA |
| Abdominal pain frequency | 30.0 (20.0, 40.0) | NA | NA |
| Abdominal bloating | 10.0 (0.0, 20.0) | NA | NA |
| Bowel habit dissatisfaction | 60.0 (60.0, 70.0) | NA | NA |
| Overall interference with QOL | 30.0 (30.0, 50.0) | NA | NA |
| HADS anxiety score | 5.0 (3.0, 10.0) | 2.0 (0.0, 3.8) | < 0.001 |
| HADS depression score | 4.0 (1.0, 7.0) | 1.5 (0.0, 3.8) | 0.009 |
| VSI score | 30.0 (19.0, 42.0) | 4.0 (0.0, 13.3) | < 0.001 |
The data are presented as the mean ± SD or the median (Q1, Q3). BSFS: Bristol stool form scale; HADS: Hospital anxiety and depression scale; IBS-D: Irritable bowel syndrome with predominant diarrhea; IBS-SSS: Irritable bowel syndrome symptom severity scale; NA: Not applicable; QOL: Quality of life; VSI: Visceral sensitivity index.