Table II.

Potential pathways of atherosclerosis and endothelial cell glycolysis.

Pathway	No.	Genes
Immune system	36	AKT1, BCL2, CD36, CD44, CTNNB1, CXCL8, CYBB, FOXO3, HGF, HIF1A, IFNG, IKBKB, IL1B, IL22, IL33, IL6, KL, MAPK1, MTOR, NOS2, NR4A1, PPBP, PRKCE, PTEN, PTGS2, RELA, SRC, STAT1, STAT3, TGFB1, TLR4, TNFSF13B, TP53, TXN, TXNIP, VEGFA
Signal transduction	30	AGTR1, AKT1, CTNNB1, CXCL8, CYBB, ESR1, FOXO3, HGF, HIF1A, IGF1R, IKBKB, IL6, KDR, KL, LEP, MAPK1, MTOR, NOTCH1, NR4A1, PPBP, PRKAA1, PRKCE, PTEN, RELA, SRC, STAT1, STAT3, TGFB1, TP53, VEGFA
Pathways in cancer	23	AGTR1, AKT1, BCL2, CDKN2A, CTNNB1, CXCL8, HGF, HIF1A, IGF1R, IKBKB, IL6, MAPK1, MTOR, NOS2, PPARG, PTEN, PTGS2, RELA, STAT1, STAT3, TGFB1, TP53, VEGFA
PI3K-AKT signalling pathway	17	AKT1, BCL2, FOXO3, HGF, IGF1R, IKBKB, IL6, KDR, MAPK1, MTOR, NR4A1, PRKAA1, PTEN, RELA, TLR4, TP53, VEGFA
Cellular responses to stress	17	CDKN2A, CXCL8, CYBB, EZH2, HIF1A, IL6, MAPK1, MTOR, NOX4, PRKAA1, RELA, SIRT1, SOD1, STAT3, TP53, TXN, VEGFA
Interleukin-4 and 13 signalling	16	AKT1, BCL2, CD36, CXCL8, FOXO3, HGF, HIF1A, IL1B, IL6, NOS2, PTGS2, STAT1, STAT3, TGFB1, TP53, VEGFA
HIF-1 signalling pathway	15	AKT1, BCL2, CYBB, ENO1, HIF1A, IFNG, IGF1R, IL6, MAPK1, MTOR, NOS2, RELA, STAT3, TLR4, VEGFA
Platelet activation, signaling and aggregation	10	AKT1, CD36, HGF, MAPK1, PPBP, PRKCE, SOD1, SRC, TGFB1, VEGFA
NGF signalling via TRKA from the plasma membrane	12	AKT1, FOXO3, HGF, KL, MAPK1, MTOR, NR4A1, PRKCE, PTEN, SRC, STAT3, TP53
Fluid shear stress and atherosclerosis	15	AKT1, BCL2, CTNNB1, CYBB, IFNG, IKBKB, IL1B, KDR, NFE2L2, PRKAA1, RELA, SRC, TP53, TXN, VEGFA
FoxO signalling pathway	11	AKT1, FOXO3, IGF1R, IKBKB, IL6, MAPK1, PRKAA1, PTEN, SIRT1, STAT3, TGFB1
PI3K/AKT activation	10	AKT1, FOXO3, HGF, KL, MAPK1, MTOR, NR4A1, PTEN, SRC, TP53
LAT2/NTAL/LAB on calcium mobilization	10	AKT1, FOXO3, HGF, KL, MAPK1, MTOR, NR4A1, PTEN, SRC, TP53