FIG 3.

Forest plot representing a multivariable Cox proportional hazards regression analysis within the residual disease group of patients. HER2-enriched (HER2-E) subtype was correlated with shorter relapse-free survival (RFS), whereas immunoglobulin G (IgG) signature was an independent good prognosis factor. The correlation to the HER2-E centroid and the IgG gene expression signature, both as continuous variables, were used for the multivariable Cox proportional hazards regression analysis. HR, hormone receptor; TH, paclitaxel plus trastuzumab; THL, paclitaxel, trastuzumab, and lapatinib; TL, paclitaxel and lapatinib.