Table 2.

Cases diagnosed as polyostotic fibrous dysplasia

Ref.	Year	Sex	Age	Location	Appendix	Treatment	Outcome
Sagmeister et al[12]	2016	F	27	Throughout the skeleton. Transverse fracture of the distal right femur	Continuous lesions, extensive bone expansion, cyst formation, cortical loss	Skin traction for 8 wk. Intensive physiotherapy for the fracture	Recovered well, returning to baseline 3 mo later
Wu et al[2]	2014	F	38	Sternum, thoracic spine, ribs, right femur, and tibia	Multiple lytic, expansile lesions, continuous pathologic fractures in the thoracic spine	Surgical therapy. Diphosphate therapy with Vit D and calcium	Completely recovered. Able to participate in daily life and work 2 yr later
Kodama et al[10]	2012	F	8	Right pelvis, bilateral femurs, and fibula	Discontinuous lesions	Thigh coxa valga osteotomy and plate fixation. Diphosphate therapy	No complaints of severe pain in lower extremity. Low bone turn-over rate
Aras et al[9]	2012	M	48	Cranium, left hemithorax, bilateral upper, lower extremities, and pelvic bones	Continuous lesions, bladder cancer	No treatment reported	No outcome reported
Boston et al[8]	1994	M	3.3	Proximal left femur and proximal left humerus	Albright-McCune syndrome, no café-au-lait pigmentation, Cushing syndrome	Bilateral adrenalectomy at 7-yr-old with steroid replacement	Cushing syndrome removed. Still with prepubertal and elevated liver enzyme
Lourenço et al[11]	2015	F	17 d	Multiple lesions with fracture in left ulna	Multiple organs involved, Café-au-lait pigmentation, mosaic GNAS gene mutation	Metyrapone therapy for Cushing syndrome	Cushing syndrome recovered. Death due to respiratory infection
The current case		F	27	Left ischium, left distal fibula, calcaneus, and talus	Discontinuous lesions, intractable bone pain, Cushing syndrome	Diphosphate therapy	Still severe pain. Difficulty participating in daily life and job

M: Male; F: Female.