Table 1.
Partial biochemical indicators in the patient with hemochromatosis
|
Item
|
Value
|
Abnormal condition
|
Normal range
|
| Routine blood tests | |||
| White blood cells (× 109/L) | 6.1 | Normal | 4.0-10.0 |
| Hemoglobin (g/L) | 92 | Decrease | 113-172 |
| Hematocrit | 0.32 | Decrease | 0.34-0.51 |
| Mean corpuscular volume (fL) | 65.2 | Decrease | 82.6-99.1 |
| Mean corpuscular hemoglobin (pg) | 19.0 | Decrease | 26.9-33.8 |
| Mean corpuscular hemoglobin concentration (g/L) | 291 | Decrease | 320-362 |
| Red cell distribution width-SD | 51.1 | Normal | 39.0-53.9 |
| Red cell distribution width-CV (%) | 23.3 | Increase | 11.9-14.5 |
| Platelet count (× 109/L) | 200 | Normal | 85-320 |
| Reticulocytes (%) | 4.2 | Increase | 0.5-2.0 |
| Anemia indicators | |||
| Ferritin (μg/L) | 1085.20 | Increase | 23.90-336.20 |
| Serum total iron blinding capacity (μmol/L) | 47.5 | Decrease | 50-77 |
| Serum iron (μmol/L) | 30.7 | Increase | 11-30 |
| Serum unsaturated iron blinding capacity (μmol/L) | 16.8 | Decrease | 25.0-52.0 |
| Transferrin saturation (%) | 64.6 | Increase | 20.0-55.0 |
| Serum folic acid (ng/mL) | 4.10 | Decrease | > 5.21 |
| Vitamin B12 (pg/mL) | 398 | Normal | 180.0-914.0 |
| Transferrin (g/L) | 1.89 | Decrease | 2.00-3.60 |
| Hemolysis test | |||
| Indirect anti-human globulin IgG test | Positive | ||
| Erythrocyte osmotic fragility test | |||
| Start hemolysis (mmol/L) | 68.4 | Decrease | 71.8-78.6 |
| Complete hemolysis (mmol/L) | 41.0 | Decrease | 54.7-58.1 |
| Biochemistry | |||
| Total bilirubin (μmol/L) | 112.5 | Increase | 3.4-25.0 |
| Direct bilirubin (μmol/L) | 14.3 | Increase | 0.0-8.0 |
| Indirect bilirubin (μmol/L) | 98.2 | Increase | 0.0-20.0 |
| ALT (IU/L) | 26 | Normal | 5-64 |
| AST (IU/L) | 17 | Normal | 5-50 |
| GGT (IU/L) | 40 | Normal | 8-60 |
| ALP (IU/L) | 68 | Normal | 34-104 |
| CHOL (mmol/L) | 2.3 | Decrease | 3.0-5.7 |
| LDLC (mmol/L) | 1.0 | Decrease | 1.3-3.6 |
| APROB (g/L) | 0.39 | Decrease | 0.60-1.10 |
| Fasting blood glucose | 5.3 | Normal | 3.8-6.2 |
| T3 (nmol/L) | 1.32 | Decrease | 1.34-3.28 |
| Routine urine tests | |||
| Bilirubin | 2+ | Negative | |
| Protein | 1+ | Negative | |
| Occult blood (RBC) | 1+ | Negative | |
| Red blood cell count (n/μL) | 31.5 | Increase | 0.0-9.9 |
| Red blood cells (n/HP) | 5.7 | Increase | 0.0-3.2 |
| The number of undissolved RBCs (n/uL), ratio (%) | 21.8 (69.1%) | ||
| C-reaction protein (mg/L) | 36.70 | Increase | 0.00-5.00 |
| Methemoglobin reduction rate (%) | 31.72 | Decrease | 75.00-100.00 |
ALT: Alanine transaminase; AST: Aspartate transaminase; GGT: Glutamyltransferase; ALP: Alkaline phosphatase; CHOL: Total cholesterol; LDLC: Low-density lipoprotein cholesterol; APROB: Apolipoprotein B; T3: Triiodothyronine; RBC: Red blood cell.