Table 2.
Pathological and clinical characteristics.
| Variable | All patients |
Female |
Male |
|||
|---|---|---|---|---|---|---|
| N | % | N | % | N | % | |
| All | 165,465 | 100.0 | 73,276 | 100.0 | 92,189 | 100.0 |
| Co-morbidity | ||||||
| None | 13,699 | 8.3 | 5337 | 7.3 | 8362 | 9.1 |
| 1–2 | 5910 | 3.6 | 2662 | 3.6 | 3248 | 3.5 |
| 3–4 | 12,702 | 7.7 | 6015 | 8.2 | 6687 | 7.3 |
| >4 | 133,154 | 80.5 | 59,262 | 80.9 | 73,892 | 80.2 |
| SEER Stage | ||||||
| Localized | 27,347 | 16.5 | 13,621 | 18.6 | 13,726 | 14.9 |
| Regional, direct extension ± lymph nodes | 19,960 | 12.1 | 8699 | 11.9 | 11,261 | 12.2 |
| Regional, lymph nodes only | 14,142 | 8.5 | 6365 | 8.7 | 7777 | 8.4 |
| Distant | 66,028 | 39.9 | 28,354 | 38.7 | 37,674 | 40.9 |
| Unknown/Unstaged | 37,988 | 23.0 | 16,237 | 22.2 | 21,751 | 23.6 |
| Types of lung cancer | ||||||
| SCLC | 20,593 | 12.4 | 9874 | 13.5 | 10,719 | 11.6 |
| NSCLC | 98,541 | 59.6 | 43,338 | 59.1 | 55,203 | 59.9 |
| Other | 46,331 | 28.0 | 20,064 | 27.4 | 26,267 | 28.5 |
| Grade | ||||||
| Undifferentiated | 12,125 | 7.3 | 5457 | 7.4 | 6668 | 7.2 |
| Poorly-differentiated | 38,048 | 23.0 | 15,884 | 21.7 | 22,164 | 24.0 |
| Moderately-differentiated | 18,916 | 11.4 | 8570 | 11.7 | 10,346 | 11.2 |
| Well-differentiated | 5794 | 3.5 | 3053 | 4.2 | 2741 | 3.0 |
| Unknown/not stated | 90,582 | 54.7 | 40,312 | 55.0 | 50,270 | 54.5 |
| Regional Nodes Positive | ||||||
| No | 20,141 | 12.2 | 9810 | 13.4 | 10,331 | 11.2 |
| Yes | 11,890 | 7.2 | 5367 | 7.3 | 6523 | 7.1 |
| Unknown | 133,434 | 80.6 | 58,099 | 79.3 | 75,335 | 81.7 |
| Histologic Type | ||||||
| Adenocarcinoma | 45,808 | 27.7 | 22,750 | 31.0 | 23,058 | 25.0 |
| Squamous/combine complex | 29,336 | 17.7 | 10,382 | 14.2 | 18,954 | 20.6 |
| Neuroendocrine | 2580 | 1.6 | 1523 | 2.1 | 1057 | 1.1 |
| Large cell | 7936 | 4.8 | 3284 | 4.5 | 4652 | 5.0 |
| Other | 15,424 | 9.3 | 6690 | 9.1 | 8734 | 9.5 |
| Unknown | 64,381 | 38.9 | 28,647 | 39.1 | 35,734 | 38.8 |
| Chemotherapy | ||||||
| No | 95,994 | 58.0 | 43,368 | 59.2 | 52,626 | 57.1 |
| Yes | 52,305 | 31.6 | 22,954 | 31.3 | 29,351 | 31.8 |
| Unknown | 17,166 | 10.4 | 6954 | 9.5 | 10,212 | 11.1 |
| Radiation Therapy | ||||||
| No | 87,238 | 52.7 | 40,605 | 55.4 | 46,633 | 50.6 |
| Yes | 65,028 | 39.3 | 27,424 | 37.4 | 37,604 | 40.8 |
| Unknown | 13,199 | 8.0 | 5247 | 7.2 | 7952 | 8.6 |
| Surgery | ||||||
| No | 117,283 | 70.9 | 51,254 | 69.9 | 66,029 | 71.6 |
| Yes | 35,725 | 21.6 | 17,087 | 23.3 | 18,638 | 20.2 |
| Unknown | 12,457 | 7.5 | 4935 | 6.7 | 7522 | 8.2 |
SCLC = small cell lung cancer, NSCLC = non-small cell lung cancer.