Fig. 7.

(A) 12-week-old male SD Rat cranial defects model and larger image; (B)The scaffolds were implanted in the cranial defect of rat and larger image; (C) Microcomputed tomography images of cranial defects implanted by different scaffolds or left empty 12 weeks postoperative; (D) Micro-CT scanning showed the coronal image of the five groups; (E) The bone volume/tissue volume (BV/TV) and Bone mineral density (BMD) were calculated by CTAn analysis software. The group without any scaffolds implanted was set as the control, also is the blank group. Data are expressed as the mean ± SD. **p < 0.01 and *p < 0.05, comparison between control group and hydrogel groups; ^#p < 0.05, comparison between different hydrogels.