Table 3.
miRNAs as Diagnostic or Prognostic Biomarkers
| miRNA | Expression | Clinical Application | References |
|---|---|---|---|
| Circulating Serum miRNAs as Biomarkers for CRC | |||
| miR-203 | ↑ | diagnosis | 106, 107 |
| miR-122 | ↑ | diagnosis | 105 |
| miR-200 family | ↑ | ||
| miR-126 | ↓ | diagnosis | 109 |
| miR-21 | ↑ | ||
| miR-210 | ↑ | ||
| miR-592 | ↓ | prognosis | 118 |
| miR-106-5p | ↑ | ||
| miR-615-3p | ↑ | ||
| miR-21 | ↑ | prognosis | 118 |
| miR-103 | ↑ | ||
| miR-93 | ↑ | ||
| miR-566 | ↓ | ||
| Exosomal miRNAs as Biomarkers for CRC | |||
| miR-96-5p | ↑ | diagnosis | 112 |
| miR-149 | ↑ | ||
| miR-17-5p | ↑ | diagnosis | 113 |
| miR-92a-3p | ↑ | ||
| miR-21 | ↑ | prognosis | 119 |
| miR-548c-5p | ↓ | prognosis | 120 |
| Stool-Based miRNAs as Biomarkers for CRC | |||
| miR-4478 | ↑ | diagnosis | 116 |
| miR-1295b-3p | ↑ | ||
| miR-135b | ↑ | prognosis | 122 |
| miR-92a | ↑ | prognosis | 126 |