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(A) The structure of nsp12-nsp7-nsp8 complex. Color marks: nsp7, magenta; nsp8-1 and nsp8-2, grey; β-hairpin, cyan; NiRAN, yellow; the interface, orange; the fingers domain, blue; the palm domain, red; the thumb domain, green. (PDB: 6M71) (B) The structure of the SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) in active form. The nsp12-nsp7-nsp8 complex bound to the template-primer RNA. (PDB: 7BV2).
