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. 2020 Nov 25;7:606461. doi: 10.3389/fmed.2020.606461

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Copyright © 2020 Nickles, Huang, Chang, Tsoukas, Sweiss, Perkins and Finn.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Volcano plots mark differentially expressed genes (orange dots) in cutaneous sarcoidosis lesions vs. control (top) and discoid lupus erythematosus lesions vs. control (bottom). The orange dots represent differentially expressed genes using the criteria of p < 0.01 and log2 (fold-change). Black, gray, and red dots are genes that do not meet the criteria of a differentially expressed gene. The common hub genes (TLR1, ITGAL, TNFRSF1B, CD86, SPI1, BTK, and IL10RA) are marked.