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. 2020 Nov 25;10:526009. doi: 10.3389/fonc.2020.526009

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Copyright © 2020 Jin, Geng, Liu, Liu, Jin, Zhao, Feng and Wei.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Gut microbiota prediction of postoperative ileus. (A) The five typically different KEGG pathways for the ileus, no-ileus, distal ileus, and distal no-ileus groups. The Wilcoxon rank-sum test. Receiving operating characteristic curve analysis was used to assess the predictive model performance of (B) EIG, DIG, and (C) Cohort 2. Statistical analysis was conducted based on the amount of Faecalibacterium and the ileus rate in (D) Cohort 2, EIG, DIG, and (E) Cohort 3 by the cutoff value of Faecalibacterium defined in Cohort 2, Chi-square test. (F) The abundance of the gut microbiota in the EIG, DIG, and new groups. **p < 0.01, ****p < 0.0001, EIG, ileus in the postoperative perioperative period; DIG, ileus within the first 6 months after hospital discharge.