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. 2020 Nov 25;10:577796. doi: 10.3389/fonc.2020.577796

Table 2.

Logistic regression models evaluating the associations between clinical variables and hypertriglyceridemia in APL and non-APL patients.

All patients Univariable analysis P-value Multivariable analysis P-value
Dependent variable Independent variable OR (95% CI) OR (95% CI)
HTG Age 1.009(0.998–1.020) 0.130 1.016(1.003–1.029) 0.019
Gender 1.246(0.889–1.747) 0.202 1.143(0.767–1.705) 0.512
BMI 1.168(1.097–1.242) <0.001 1.160(1.087–1.238) <0.001
Leukemia type 3.185(2.154–4.710) <0.001 3.558(2.312–5.477) <0.001
Leukemia type Age 1.025(1.013–1.038) <0.001 1.030(1.012–1.048) 0.001
(non-APL) Gender 1.259(0.872–1.816) 0.219 1.543(0.906–2.628) 0.110
BMI 0.980(0.924–1.040) 0.507 0.994(0.910–1.086) 0.897
TG 0.555(0.446–0.689) <0.001 0.547(0.414–0.723) <0.001
WBC 1.020(1.013–1.027) <0.001 1.024(1.014–1.034) <0.001
PLT 1.014(1.010–1.019) <0.001 1.019(1.013–1.026) <0.001
LDH 1.001(1.000–1.001) 0.001 1.000(1.000–1.001) 0.161
APL patients Univariable analysis P-value Multivariable analysis P-value
HTG Age 1.021(1.007–1.035) 0.002 1.026(1.008–1.044) 0.004
Gender 1.564(1.039–2.354) 0.032 1.222(0.715–2.088) 0.463
BMI 1.165(1.080–1.257) <0.001 1.149(1.053–1.254) 0.002
WBC 1.026(1.012–1.040) <0.001 1.022(1.005–1.040) 0.011
LDH 1.001(1.000–1.002) 0.001 1.001(1.000–1.001) 0.122
transcript isoform

APL, acute promyelocytic leukemia; non-APL, acute myeloid leukemia exclude of APL; HTG group, high triglyceride group ≥ 1.70 (mmol/L); BMI, body mass index; WBC, white blood cell; TG, triglyceride concentration; PLT, platelet count; LDH, lactate dehydrogenase; OR, odds ratios; CI, confidence interval; PML-RARα, promyelocytic leukemia-retinoic acid receptor alpha.